Jerry Shapiro and Keith D. Kaufman (2003) Use of Finasteride in the Treatment of Men With Androgenetic Alopecia (Male Pattern Hair Loss) J. Invest. Dermatol. Vol.8 No.1, 20-23.
This study compared the clinical outcomes of finasteride 1mg/day over 1 and 5 years in patients with male pattern hair loss (MPHL) to a placebo group. The study involved a substantial number of participants and evaluated hair loss improvement using photographic analysis. This study was a collaborative effort between the Department of Dermatology at the University of British Columbia in Vancouver, Canada, and Merck Research Laboratories in New Jersey, USA (the developer of finasteride).
Key Highlights:
12-month vs 60-month treatment comparison: The proportion of patients showing hair loss improvement was slightly lower at 60 months compared to 12 months of treatment.
Approximately 40% of patients experienced no improvement or worsening of hair loss after 60 months, while 50% showed improvement.
Self-reported satisfaction: Self-reported satisfaction was higher in patients taking finasteride for 60 months compared to 12 months.