#17 A Study on the Changes in Inflammatory Markers in the Serum of Children with Alopecia Areata

Katarzyna Tabara, Magdalena Koztowska, Anna Jedrowiak, Wojciech Bienias, Andrezej Kaszuba (2019) Serum concentrations of selected proinflammatory cytokines in children with alopecia areata. Advances Dermatol. Allergol. V1: 63-69.

Alopecia areata (AA) is a common autoimmune disease that causes patchy hair loss on the scalp, face, and sometimes other body areas. Researchers investigated the potential role of pro-inflammatory cytokines in AA development in children. They measured serum levels of IL-6, IL-15, IL-17A, and IFN-γ in 42 children with AA (13 males and 29 females, all under 18 years old). A control group consisted of 37 healthy children.

 

Key Highlight:

Serum levels of IL-6, IL-15, IL-17A, and IFN-γ were significantly elevated in children with AA compared to controls (Figure 1).