{"id":14745,"date":"2024-04-12T09:10:29","date_gmt":"2024-04-12T00:10:29","guid":{"rendered":"https:\/\/blmo.co.kr\/10-rebuttal-letter-on-annurca-apple-extract-for-hair-growth\/"},"modified":"2024-07-10T18:01:28","modified_gmt":"2024-07-10T09:01:28","slug":"10-rebuttal-letter-on-annurca-apple-extract-for-hair-growth","status":"publish","type":"post","link":"https:\/\/blmo.co.kr\/en\/10-rebuttal-letter-on-annurca-apple-extract-for-hair-growth\/","title":{"rendered":"#10 Rebuttal letter on Annurca Apple Extract for Hair Growth"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"14745\" class=\"elementor elementor-14745 elementor-14457\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-27840c92 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"27840c92\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-348ca2d1\" data-id=\"348ca2d1\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1b7bb3d2 elementor-widget elementor-widget-text-editor\" data-id=\"1b7bb3d2\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Scott W. Keith, Andrew W.Brown, Moonseong Heo, Steven B. Heymsfield, and David B. Allison (2019) Re:\u201cAnnurca Apple Nutraceutical Formulation Enhances Keratin Expression in a Human Model of Skin and Promotes Hair Growth and Tropism in a Randomized Clinical Trial\u201d by Tenore et al. J. Med. Food 22(12) 1301-1302.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-6ed22b3 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"6ed22b3\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-94ae866\" data-id=\"94ae866\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-c0be36c elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"c0be36c\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-80ecdae\" data-id=\"80ecdae\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-ca73f71 elementor-widget elementor-widget-image\" data-id=\"ca73f71\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31718391\/\" target=\"_blank\">\n\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"508\" height=\"722\" src=\"https:\/\/blmo.co.kr\/wp-content\/uploads\/2024\/04\/10\ubc88\uc378\ub124\uc77c-e1720602075551.png\" class=\"attachment-medium_large size-medium_large wp-image-14470\" alt=\"\" \/>\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-64b756f\" data-id=\"64b756f\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-8bfe23b elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"8bfe23b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>This rebuttal letter, published in the same journal as the original research on Annurca apple extract for hair growth, presents critiques from five experts from the University of California and various research institutions. The paper is relatively short, spanning two pages, and focuses on two main concerns:<\/p>\n<p>&nbsp;<\/p>\n<p>Key Highlights:<\/p>\n<p><strong>Flawed Randomization: <\/strong>The study did not randomly assign participants to either a placebo group or an active Annurca apple extract (AMS) group. The lack of a true placebo control group makes it impossible to distinguish the actual effects of AMS from other factors.<\/p>\n<p>&nbsp;<\/p>\n<p><strong>No True Double-Blinding:<\/strong> The investigators were aware of which patients received the placebo and which received the active treatment due to the non-concurrent placebo design. This knowledge could introduce bias in how patients were managed and how results were interpreted.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-48f87d5 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"48f87d5\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-c731983\" data-id=\"c731983\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-9623424 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"9623424\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-ae2ff12\" data-id=\"ae2ff12\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-fa7cb6c elementor-widget elementor-widget-spacer\" data-id=\"fa7cb6c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Scott W. Keith, Andrew W.Brown, Moonseong Heo, Steven B. Heymsfield, and David B. Allison (2019) Re:\u201cAnnurca Apple Nutraceutical Formulation Enhances Keratin Expression in a Human Model of Skin and Promotes Hair Growth and Tropism in a Randomized Clinical Trial\u201d by Tenore et al. J. Med. Food 22(12) 1301-1302. This rebuttal letter, published in the same [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":14470,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"footnotes":""},"categories":[64],"tags":[],"class_list":["post-14745","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-papers-on-hair-loss"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/blmo.co.kr\/en\/wp-json\/wp\/v2\/posts\/14745","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blmo.co.kr\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blmo.co.kr\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blmo.co.kr\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/blmo.co.kr\/en\/wp-json\/wp\/v2\/comments?post=14745"}],"version-history":[{"count":2,"href":"https:\/\/blmo.co.kr\/en\/wp-json\/wp\/v2\/posts\/14745\/revisions"}],"predecessor-version":[{"id":15670,"href":"https:\/\/blmo.co.kr\/en\/wp-json\/wp\/v2\/posts\/14745\/revisions\/15670"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/blmo.co.kr\/en\/wp-json\/wp\/v2\/media\/14470"}],"wp:attachment":[{"href":"https:\/\/blmo.co.kr\/en\/wp-json\/wp\/v2\/media?parent=14745"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blmo.co.kr\/en\/wp-json\/wp\/v2\/categories?post=14745"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blmo.co.kr\/en\/wp-json\/wp\/v2\/tags?post=14745"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}