{"id":14751,"date":"2024-04-12T10:14:18","date_gmt":"2024-04-12T01:14:18","guid":{"rendered":"https:\/\/blmo.co.kr\/13-research-paper-on-finasteride-and-kidney-health-animal-study-highlights-potential-risks-for-individuals-with-compromised-kidney-function\/"},"modified":"2024-07-11T09:18:30","modified_gmt":"2024-07-11T00:18:30","slug":"13-research-paper-on-finasteride-and-kidney-health-animal-study-highlights-potential-risks-for-individuals-with-compromised-kidney-function","status":"publish","type":"post","link":"https:\/\/blmo.co.kr\/en\/13-research-paper-on-finasteride-and-kidney-health-animal-study-highlights-potential-risks-for-individuals-with-compromised-kidney-function\/","title":{"rendered":"#13 Research Paper on Finasteride and Kidney Health: Animal Study Highlights Potential Risks for Individuals with Compromised Kidney Function"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"14751\" class=\"elementor elementor-14751 elementor-14493\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-27840c92 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"27840c92\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-348ca2d1\" data-id=\"348ca2d1\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1b7bb3d2 elementor-widget elementor-widget-text-editor\" data-id=\"1b7bb3d2\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Mirza Saim Baig, Agnieszka Kolasa-Wolosiuk, Anna Pilutin, Krzysztof Safranow, Irena Baranowska-Bosiacka, Joanna Kabat-Koperska and Barbara Wiszniewska (2019) Finasteride-Induced Inhibition of 5\u03b1-Reductase Type 2 Could Lead to Kidney Damage-Animal, Experimental Study. Int. J. Environ. Res. Public Health. 16, 1726.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-6ed22b3 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"6ed22b3\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-94ae866\" data-id=\"94ae866\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-c0be36c elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"c0be36c\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-80ecdae\" data-id=\"80ecdae\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-ca73f71 elementor-widget elementor-widget-image\" data-id=\"ca73f71\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31100850\/\" target=\"_blank\">\n\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"508\" height=\"722\" src=\"https:\/\/blmo.co.kr\/wp-content\/uploads\/2024\/04\/13\ubc88\uc378\ub124\uc77c-e1720657100157.png\" class=\"attachment-medium_large size-medium_large wp-image-14495\" alt=\"\" \/>\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-64b756f\" data-id=\"64b756f\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-8bfe23b elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"8bfe23b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>This summary examines a study investigating the potential link between finasteride and kidney damage. Finasteride is a medication commonly used to treat enlarged prostate (BPH) and hair loss by blocking the conversion of testosterone to DHT. While generally considered safe, concerns exist regarding its impact on kidney health.<\/p>\n<p>&nbsp;<\/p>\n<p>Key Highlights:<\/p>\n<p><strong>Hormone Levels:<\/strong> Finasteride administration (5 mg\/kg body weight) for 4-5 months significantly reduced blood levels of testosterone, dihydrotestosterone, and 17\u03b2-estradiol in rats.<\/p>\n<p>&nbsp;<\/p>\n<p><strong>Androgen Receptor Expression:<\/strong> Finasteride treatment also led to a marked decrease in androgen receptor expression in rat kidneys.<\/p>\n<p>&nbsp;<\/p>\n<p><strong>Kidney Damage Indicators:<\/strong> Several indicators of kidney damage were observed in finasteride-treated rats, including altered intercellular junction proteins, increased apoptosis, elevated IL-6 expression and fibrosis progression<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-48f87d5 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"48f87d5\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-c731983\" data-id=\"c731983\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-9623424 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"9623424\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-ae2ff12\" data-id=\"ae2ff12\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-fa7cb6c elementor-widget elementor-widget-spacer\" data-id=\"fa7cb6c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Mirza Saim Baig, Agnieszka Kolasa-Wolosiuk, Anna Pilutin, Krzysztof Safranow, Irena Baranowska-Bosiacka, Joanna Kabat-Koperska and Barbara Wiszniewska (2019) Finasteride-Induced Inhibition of 5\u03b1-Reductase Type 2 Could Lead to Kidney Damage-Animal, Experimental Study. Int. J. Environ. Res. Public Health. 16, 1726. This summary examines a study investigating the potential link between finasteride and kidney damage. Finasteride is a [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":14495,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"footnotes":""},"categories":[64],"tags":[],"class_list":["post-14751","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-papers-on-hair-loss"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 4.9.8 - aioseo.com -->\n\t<meta name=\"description\" content=\"Mirza Saim Baig, Agnieszka Kolasa-Wolosiuk, Anna Pilutin, Krzysztof Safranow, Irena Baranowska-Bosiacka, Joanna Kabat-Koperska and Barbara Wiszniewska (2019) Finasteride-Induced Inhibition of 5\u03b1-Reductase Type 2 Could Lead to Kidney Damage-Animal, Experimental Study. Int. J. Environ. Res. Public Health. 16, 1726. This summary examines a study investigating the potential link between finasteride and kidney damage. 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